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In broad terms, pharmacodynamics discusses the interactions of chemicals with biological receptors, and pharmacokinetics discusses the absorption, distribution, metabolism, and excretion of chemicals from the biological systems. Pharmacology is not synonymous with pharmacy and the two terms are frequently confused. Pharmacology deals with how drugs interact within biological systems to affect function.
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Dioscorides' De Materia Medica is often said to be the oldest and most valuable work in the history of pharmacology.[2] The origins of clinical pharmacology date back to the Middle Ages in Avicenna's The Canon of Medicine, Peter of Spain's Commentary on Isaac, and John of St Amand's Commentary on the Antedotary of Nicholas.[3] Clinical pharmacology owes much of its foundation to the work of William Withering.[4]
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